The KNOTTIN database

Pre-compiled sequence alignments

Access: 88983
Comments:
Below are manually checked pre-compiled alignments.
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Agouti-related

Alpha-amylase inhibitor

Algae

Bacteria

Bug

Ciliate

Conotoxin1

Conotoxin2

Conotoxin3

Cyclotide

Fungi1

Fungi2

Gurmarin-like

Horseshoe crab

Insect1

Insect2

Maize

Metallocarboxypeptidase inhibitor

Mycetozoa

Plant antimicrobial

Plant defensin

Plant toxin

Plant toxin2

Scorpion1

Scorpion2

Serine protease inhibitor1

Serine protease inhibitor2

Serine protease inhibitor3

Spider

Sponge

Trematoda

Trichoplax

Virus1

Virus2

Water flea

Insect2
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#=Position                     ----+---10----+---20----+---30----+---40----+---50----+---60----+---70----+---80----+---90----+--100----+--110----+--120----+--130----+--140----+--150----+--160----+--170----+--180----+--190----+--200----+--210----+--220----+--230----+--240----+--250----+--260----+--270----+--280----+--290----+--300----+--310----+--320----+--330----+--340----+--350----+--360----+--370----+--380----+--390----+--400----+--410----+--420----+--430----+--440----+--450----+--460----+--470----+--480----+--490----+--500----+--510----+--520----
E2B985_HARSA                   ----------------------------------------------------------------MAKFLALLFVALVALA-------------------------LVEACAPPGMMCS-SDSDCCGT--FVCNPWA---------G----RCTGAKWNGPYGNDNGNGNGRPW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E9ILQ3_SOLIN                   --------------------------------------------------------MNQALMNHPYIPVTCYAKYDTAEKMAKLMMYVFVA---LLAASLIMAAPDKATCKRHGDPCV-GSSECCPN--MRCHMYA---------N----RCQVIITEEELMAQREKILGRKGKDY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F0JAR7_DROME                   ---------------------------------------------LSIAFNIVIRMLLGMAIAFPTHQFVPHIPYGMDDFYPFLARNSTDVLPLSTNLTQIERLGWADKCVQFRNKCT-LAEHCCSLR---CLKR-------------IYRCIT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B5DVZ9               ----------------------MNATGLLLLMGLALSLQLILMGPTSC-APMSDELESPSSIKEIGGLAAFAYTRKKVAKTPPKTNLIMPP---SKNMTRRQRMEYADDCEPLGMVCKFAE-QCCTK---ACMVAT---------R----RCAFVGS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B4G5Z8               ----------------------MNATGLLLLMGLALSLQLILMGPTSC-APMSDELESPSSIKEIGGLAAFAYTRKKVAKTQPKTNLIMPP---SKNMTRRQRMEYADDCEPLGMVCKFAE-QCCTK---ACMVAT---------R----RCAYVGS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B5DVZ0               ----------------------MNATGLFLLMGLALCLELFLLGPT-CGAPLSEELEAPSPIKEIGGLAAFAYSRKKLPKKQGQKNLIMPL---SKNMTRRQRMEYADNCEPLGMVCKFAE-QCCTR---VCMVAT-------------KRCSYVGNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B4G5W9               ----------------------MNATGLFLLMGLALCLELFLLGPTSC-APLSEELEAPSPIKEIGGLAAFAYSRKKLPKKQGQKNLIMPR---SKNMTRRQRMEYADNCEPLGMVCKFAE-QCCTR---VCMVAT-------------KRCSYVGNS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B5DVZ8               ----------------------MNSGGILLVMGLVLFLGVILNRSTSG-----------APVLDELDSPSVIKEFGGLAEFFSQRRKPPRQMPLSKNMTREQRIEWNKNCELYGTPCELAE-QCCTR---ICLVAT---------R----ECGAPAVPIKPWS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B4G5Z7               ---------------------------MGLVLFLGVILNRSTSG---------------APVLDELDSPSVIKEFGGLAEFFSQRRKPPRQMPLSKNMTREQRIEWNKNCELYGTPCEMAE-QCCTR---ICLVAT---------R----ECGAPAVPIKPW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E2B7Z7_HARSA                   --------------------------------------------------------------MSRKGILSISLISSRRTS---------------------LIYLFRRACIRRGSNCDHRPKDCCYS--SSCRCNL---------WGSNCRCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_E9ISS2               ----------------------------------------------HFTFAEDVDYLQGDDLSEYPSDNALENLLRVAQKRTSSIN------------------LFRRACIRRGGDCYHRRKDCCYS--SSCRCNL---------WGSNCQCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
B4NHX5_DROWI                   --------------------------------------------------------MAPDDSLINQFQQQMEGTSPYVYREMERVENIQAI---KRLPVPSRFPVYRRVCIPRSGLCDNHPNDCCFN--SSCRCNL---------WGNNCRCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B0W1P2               ----------------------------------------MQFLGEGRKFDDLSEGRYLKALAIGEETNEAEDTDKSLTDDSILDNMLQQG----ASKRSSLIQVYRRACIRRGGNCDHRSNDCCYN--SSCRCNL---------WGSNCRCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_A0NF98               ---------MNKCTVGR--------------LLICLLIAFIAGAHGASNYLYESEERYPVPASNLLEDDVEDSDRASLTDDGVLENYLQGG---GASKRSSLIQVYRRGCIPRGGNCDHRSNDCCHN--SSCRCNL---------WGSNCRCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_D2A1J7               MERMPYGGEALSCSITAPRRRGRPFIGENPSVTLHSVFSLVFVRIISRIMKYTWLVLAACMVLVLAELLPGAAAGPYLDDDEGLPSDDDYT---ENAIDRLLQSAQKRACVRRGGNCDHRPNDCCYN--SSCRCNL---------WGSNCRCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E2ADU7_CAMFO                   ------------------------------------------------MRSWLLWLSLLLVVLADRGFASPYFDDGEDVGDFQGGDSSDYT---DNALENLMRAAQKRACIRRGGNCDHRPKDCCYS--SSCRCNL---------WGSNCQCQRMGLFQKWG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
POI_MUSDO                      ---------------------------------------------------------------------------------------------------AVTDNEIVPQCLANGSKCYSHD-VCCTK---RCHNY-------------AKKCVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B6A8J5               ------------------------------------------------------------RSGAIEKIDAPEAPAVAQPN---------------I-------VSNEFKCAKLGEDCIFHN-DCCSR---ACLGYS-------------KKCVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B4LSN4               ---------------------------------------------------------------MLGDLVMSPSMSSEQIN----------------------ILKNKQPCKGIGMTCDIAE-DCCTL---LCLKR-------------YNECVI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_B4HM35               -------------------------------------------------------------------MSSISTIIGLCLLFFILSN----------------VDVNGQKCSPVDGVCYMHS-DCCSR---RCLTYG-------------SRCGYPAHRLKKTYLSADEFQSIKRQSASSFN----------------------------------------------------------------------------------------------------------------------DEVKVIGLPSESEPSNVVFKIDS---------------------PAKCHNVGEPSQIEALPAGKDSS-----------------------------------------------------------GKDAKLPLISKPPLQQQHNPLNQDEVTMFTNMFLSLFRGVADYRNMVAAESVQSVWLSPPVVDFSHRLFAS----------------------------
UniRef100_B4QZ82               -------------------------------------------------------------------MSSISTIIGLCLLFFILSN----------------VDVNGQKCSPVFGNCNMHS-DCCSG---KCLTYG-------------SRCGYPAHRLKKTYLSADEFQSIKRQSASSFN----------------------------------------------------------------------------------------------------------------------DEVKVIGLPSESEPSNVVFKIDS---------------------PAKCRNVGEPSQIEALPAGKDSS-----------------------------------------------------------GKDAKLPLISKPPLQQQLNPLNQDEVTMFTNMFLSLFRGVADYRNMVAADSVQSVWQSPPVVDFSHRLFAS----------------------------
UniRef100_B3NZX7               -------------------------------------------------------------------MSPIPTIIGLYLSLFILSN----------------VDAYSTKCSPVFGVCYMHT-DCCSG---RCLTY-------------GSYCGYPAHRLTTTYLSPNEFASIKKKTAKSINDE----------------------------------------------------------------------------------------------------------------------VKVFGLPSESEPSNDVFDVDSNP-----------------HSAVKCYNVGEPSQIGALPAGKDSS-----------------------------------------------------------AKDTKLPLISKPPLQQQLNPLNQDEVTMFTNMFLSLFRGVADYRNMVAAESVQSVWQSPPVVDFSHRLFAS----------------------------
UniRef100_Q6IJI1               -------------------------------------------------------------------MSSISTIIGLCLLFFMLSN----------------VDAYGQKCSPVFGNCNMHT-DCCSG---KCLTY-------------GSRCGYPAHRLKETYLSASEFQSIKKQRAHSNNDE----------------------------------------------------------------------------------------------------------------------VKVIGLPSESEPSNVFFKIDS---------------------AAKCHNVGEP--------------------------------------------------------------------------VGWAIIVEFKPLQQQLNPLNQDEVTMFTNMFLSLFRGVADYRNMVAADSVQSVWQSPPVVDFSHRLFAS----------------------------
B3DNG2_DROME                   ----------------------------------------------------------------SEKMSSISTIIGLCLLFFMLSN----------------VDAYGQKCSPVFGNCNMHT-DCCSG---KCLTY-------------GSRCGYPAHRLKETYLSASEFQSIKKQRAHSNNDE----------------------------------------------------------------------------------------------------------------------VKVIGLPSESEPSNVFFKIDS---------------------AAKCHNVGEP--------------------------------------------------------------------------------------------CSRGEECCNLRCHSYMHRCVT----------------------------------------------------------
UniRef100_F1DKP9               --------------------------------------------------------------------SSISMIIGLCLLFFMLSN----------------VDAYGQKCSPVFGNCN-MHTDCCS---GRCLTYG-------------SRCGYPAHRLKETYLSASEFQSIKKQRAHSNNDE----------------------------------------------------------------------------------------------------------------------VKVIGLPSESEPSNIFFKIDS-----------------------------------------------------------------------------------------------------------------AAKCHNVGEPCSRGEECCNLRCHSYMHRCVT----------------------------------------------------------
UniRef100_F1DKP8               --------------------------------------------------------------------SSISTIIGLCLLFFMLSN----------------VDAYGQKCSPVFGNCN-MHTDCCS---GRCLTYG-------------SRCGYPAHRLKETYLSASEFQSIKKQRAHSNNDE----------------------------------------------------------------------------------------------------------------------VKVIGLPSESEPSNIFFKIDS-----------------------------------------------------------------------------------------------------------------AAKCHNVGEPCSRGEECCNLRCHSYMHRCVT----------------------------------------------------------
UniRef100_E1JIS4               -------------------------------------------------------------------MSSISTIIGLCLLFFMLSN----------------VDAYGQKCSPVFGNCN-MHTDCCS---GKCLTYG-------------SRCGYPAHRLKETYLSASEFQSIKKQRAHSNNDE----------------------------------------------------------------------------------------------------------------------VKVIGLPSESEPSNVFFKIDS-----------------------------------------------------------------------------------------------------------------AAKCHNVGEPCSRGEECCNLRCHSYMHRCVT----------------------------------------------------------
B4PKU4_DROYA                   -------------------------------------------------------------------MSSLPTIIGLYIFFFITFSN---------------VHAYSTKCSPMLGVCNMHT-DCCSG---RCLTYG-------------SYCGYPAQRLTKTYLRPNEFTSIKKEQSKSINDEDLEEFALDR--------------------------------------------------------------------------------------------------------------------------EVLRTKQVLRDRMADYVYNGFWFSPEATYDRKCIKLAEQRVSG-------------------------------------------------------------------------------------KVTVELAPGYCRGVSMNVHGGYVPQDAVRVKAEAEKLIK-------------------------------------------
UniRef100_D1FQ65               -----------------------------------------MTYPLKRQQKPMASHWSCRSMAVTLVLGWCVLANWPTVR------------------------SEPQQCTKIGDYCTHHD-ACCSK---SCPSF-------------VGKCVSNSQLVAPDLPRPDVKPSIPPTPSGWG-----------------------------------------------------------------------------------------------QCVRVGDWCQSASDCCSQICNITTRLCATYNFFQLLFPQFVPQYP------------IPTVPMPVKPIS--------------------------------------------------------------------------------------------QQCLTQGSKCNNHKECCTNYCNFYARRCVD----------------------------------------------------------
UniRef100_B4M149               ----------------------------------------------------------------------MRHVQARQDN------------------------IVKRNCSENGQYCQMHM-DCCSR---KCMTY-------------MYKCAPRVPEKYPESNGSPTGLNSLPDFWWP------------------------------------------------------------------------------------------------------------LYHANIPLNEDLEIVTLQDDKTTTRTELVENSSQSAEIAGIAYDIVNPSSTAPTSSA--------------------------------------------------------------------------------------------PRCKRVGDVCSVSSECCTMRCHTYLHKCVT----------------------------------------------------------
UniRef100_B4G600               -----------------------------------------------------------------MSMSIARFGFYLCILGLVAAHFE----------------REGLTCKANGEYCQMHS-DCCSR---KCMTY-------------LNVCARRIDEGFSLETPHQSNSIYDIDVKQSSKEFPD---------------------------------------------------------------------------------------------------------IVDIVTLATESKQTPQTEQGRQCQPVGGQIITSSPSIQCQMHSDCCSRKCMTYLNVCARRIDEGFSLETPHQSNSIYDIDVKQSSKEFPDIVDI-----------------------------------------VTLATESKQTTTDGAGQAVPAGRWTAEIISPHPSFSARCIG-TAARGKCMTYLSVCAKKIARAFSRAVLPQSNSTQKNDAKQSAHQFPDKKSVRTPQEE
F4WVG0_ACREC                   -------------------------------------------------------------MLIPRVVPSASTSYTLESSGSRDRAPKPS----------------TLLCHEP---CIGVL-ACCPDT-TFCFFLASIIIVVANKQQIAEGCWLAGSRTVRQGKARQGKARQGKARQGNGKAMQAVAEYRG-----------------------------------------------------------------------------------------DMPCLPAGATTRLTFVRPVLRSGPAGTNETPDLPTRSAVRLVPLRSELELVVEFAIGLVLELDATKRSRKLDVSLDRNAYNSVNSVETNVRYGITLENPGGRRAKTKEPGGSEWSRVDRAICVDRMRSYGRIREERRAGAANDRNGHVAPYVYEMRGLLLTSSLVLARSSQEWNKREPRAPRERKVELLIVLVSAQLASV--------------------------------------------
UniRef100_B0W1Y0               -------------------------------------------------------------MKQLILLLTVAAVVGHSQA------------------------QGNRKCAANGEYCLTHS-ECCSG---SCLSF-------------SYKCVPVPPSASVGTTFVPVTVDTANRFGE---DDGGASITQKTCAKNGEYCLTHSECCSGSCLSFSYKCVPIPGQPAQPGETAQQPQRPPLQTSTTVDVG---NRVGEGEQGSTVPVTHLTPPPPKKCAALGEYCLTSADCCSKSCLSFSYKCVGNYDLG-SQVTQQGIPVQRPSGAGNSGSIETSNRFGGSDSNRQCTANGLYCFHSGECCSGACFKSYCATEIKLGVPESDLTRPSPANGPYVQVNSLDDLITRFGGGGQQADSSVSAS-------------------SKLGNLCSRQEDCCSHRCHSYRRKCVT----------------------------------------------------------
UniRef100_Q5BN34               ----------------------------------------------------------MHQQILLFVIVTLSCLYFCEAQ------------------------TDKKQCAKNNEYCLTHR-DCCSG---SCLSF-------------SYKCVPVPASASEGFISVPVKPVPIDTANRFGADDGGASLTQKTCALNGEYCLTHMECCSGNCLTFSYKCVPLSPSDSAMTGPLYSTPQISMVNFTNRIG-----------DETSSILTTTHTSVPKMCAKIGEYCLTSSECCSKSCLSFAYKCVNRYDLSVVADPNLPVTSTYTSNRFGGTVDETS------TGTPKCTSNGLYCVHNKDCCSGACYKSVCSTEIRVGVLESELTRPSVINGPYIQVQNLDDLITRYSGQISTTEQSVTHIEG---------------RCKAIGDSCTRHENCCSSNCHSYRGKCVT----------------------------------------------------------
Q170Q5_AEDAE                   ------------------------------------------------------------MKQLILLLVVAVALVDYSQA------------------------QGNRKCAANGEYCLTHS-ECCSG---SCLSF-------------SYKCVPVPPSASVGTVFVPAPIETDNRFGGG--DDSGTSITQKTCAKNGEYCLTHAECCSGSCLSFSYKCVPTQPGTSSVQQQPQQPVRPQAFPTTIRTTTVDLGNRIGEEGQSSSTTTAATTARPQKCAAVGEYCLTAADCCSRSCLSFSYKCVQNYDLGTQQLTSSGIPVQLPVGGSSINTIDTANRFGGGGSERQCLANGHACFYGQECCSGACFRSFCATQIHLGIPESALTRPSAVNGPFVQVNSLDELITRFGGGSDANHARDSSASASLKRANIGARSGVEKQCAVVGEGCSRQEDCCSMRCHSYRRKCVT----------------------------------------------------------
UniRef100_Q170Q6               ------------------------------------------------------------MKQLILLLVVAVALVDYSQA------------------------QGNRKCAANGEYCLTHS-ECCSG---SCLSF-------------SYKCVPVPPSASVGTVFVPAPIETDNRFGGG--DDSGTSITQ------------------------------------------------------------------------------------KTCAKNGEYCLTAADCCSRSCLSFSYKCVQNYDLGTQQLTSSGIPVQLPVGGSSINTIDTANRFGGGGSERQCLANGHACFYGQECCSGACFRSFCATQIHLGIPESALTRPSAVNGPFVQVNSLDELITRFGGGSDANHARDSSASASLKRANIGARSGVEKQCAVVGEGCSRQEDCCSMRCHSYRRKCVT----------------------------------------------------------
UniRef100_Q6IJI2               -------------------------------------------------------------------MLIARLAFLVSILGIVVGFQKLDS---TSSPTTTSTMRSAPYCQPSGGYCKSHA-DCCST---MCLTQ-------------LGQCS---------------------------------------------------------------------------------------------------------------------------------------------------------PKRGDQCKHVG----------------------------SCKWQAGS---------------------------------------------------------------------------------------------SWMQVGLVFSHRLHFPRCTASFGSAQWEMAEGFGC-------------------------------------------
D9HQ83_9NEOP                   ------------------------------------------------------------------MTFIITLAMRLPLLLILYLTLIVIQSN---------------ACKYDTATCF-SHEECCS---TCCIG---------------GSCENAFRSCIYK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
F0JAT5_DROME                   ------------------------------------------------------------------KMLIARLGFLLCSLGLATAI-----------------------CQTNGESCKSHA-DCCST---MCLTQL-------------GQCSPKRGDQW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_C4NAP5               -------------------------------------------------------------------MLIARLGLLLCSLGLATAI-----------------------CQPNGQSCKSHA-DCCST---MCLTQL-------------GQCSPKRGDQW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_E1JIS3               -------------------------------------------------------------------MLIARLGFLLCSLGLATAI-----------------------CQPNGQSCKSHA-DCCST---MCLTQL-------------GQCSPKRGDQW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_Q2MJU0               ---------------------------------------------------------------------MSKLLVVLCIAFIAMT--------------------VASACSPPGFFCQTDD-DCCFTKLFRCLEI-------------VGRCVKRNVTVASTTALPTNSINL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_E9I8Q5               --------------------------------------------------------------MKCLVFALIVMVALNGIAAAPSYE------------------NSKAVCTPWLGYCQ-LTDQCCRD--LICLTY-------------AAKCVPG----KIIDDKRPIGDGPFPPTGK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
E2AMT8_CAMFO                   --------------------------------------------------------------MNKCLVFALIAMTSINVVVTSTTT------------------NPEPICIPWLGKCL-LTEQCCRD--LVCMRY-------------LAKCIPG----QIWNDNRPIGDGPFPPKIKTLFN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
UniRef100_E9ILQ4               --------------------------------------------------------------MKFVIFAIFVMIAMAMTQ------------------------AETQQCSPWLQLCH-VKEDCCRY--LECSTY-------------QAKCVPQSGLIIPGRDKRPLGPGPYPPNVPKEYLEE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------